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This review assessed whether herbal medicines can reduce cholesterol. There was limited evidence to suggest that the herbal medicines assessed might lower cholesterol. Further research is warranted to establish the therapeutic value of these herbs in the treatment of hypercholesterolaemia. The authors' cautious conclusions seem consistent with the poor quality evidence presented.
MEDLINE, EMBASE, CINAHL, AMED, the Cochrane Library (Issue 2, 2001) and CISCOM were searched from their inception to May 2001. Departmental files and the reference lists of identified papers were checked, and experts and manufacturers were contacted. No language restrictions were applied.
The inclusion criteria specified monopreparations of herbal medicinal products with hypocholesterolaemic properties, administered as supplements. The specific interventions in the included studies were: guggul, fenugreek seeds, fenugreek leaves, red yeast rice, artichoke, eggplant, arjun, Asian ginseng, holy basil, yarrow, silymarin. Studies using garlic were not included. Some studies included concomitant low-fat or low-cholesterol diets. The comparison groups varied both within herbal medications and between medications. The comparison groups were active treatments, placebo or 'control'. Brief details of the comparators were given in the paper. The length of treatment ranged from a single dose to 24 weeks.
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The inclusion criteria for the participants in the review were not specified. The participants included healthy volunteers and those diagnosed variously with hypercholesterolaemia, hyperlipidaemia, coronary artery disease, non insulin-dependent diabetes mellitus, dyslipidaemia, human immunodeficiency virus-related dyslipidaemia, and obesity. No further details were given.
The inclusion criteria were not specified in terms of the outcomes of interest. Those reported were changes in total cholesterol (TC), high-density lipoprotein cholesterol and low-density lipoprotein cholesterol. Safety and adverse effects were also discussed.
If you’ve been diagnosed with high cholesterol, your doctor may prescribe statins, a medicine used to lower LDL cholesterol. Your doctor may also suggest changes to your diet and exercise routine. Dietary changes could include foods particularly good for lowering cholesterol.
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Your liver makes cholesterol. You can also get it from certain foods that contain it — but not as much as from foods that contain saturated and trans fats. These types of fat cause your liver to produce extra cholesterol.
Niacin is a B vitamin. Doctors sometimes suggest it for patients with high cholesterol or heart concerns. It increases the level of good cholesterol and reduces triglycerides, another fat that can clog arteries. You can get niacin from foods, especially liver and chicken, or from supplements.
Food manufacturers have begun adding phytosterols to prepared foods, such as margarine and yogurt. That’s right: you can eat a food containing cholesterol and counteract the effect of that cholesterol, at least a little, at the same time!
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